Do the refs know how much impact a flag could have at the time they throw it?

Was that ref aware that if he threw that flag, it basically would end the game? Do they "think" about it before the pulling the flag out?

I am guessing they know exactly what the impact will be before they toss the flag.

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#HelmetHornsMatter

“Well, the color is good, I like the metallic blue,” Youngblood recently said while laughing, via NFL Journal. “The horn is terrible. It looks like a ‘C.’ When I first saw it on the logo I honestly thought it was a Charger logo.

“Now when I see it on the helmet, it just isn’t a ram horn. There is no distinct curl like a mature ram horn. I don’t know how the Rams could get that wrong. That is your symbol and it has been for what? Seventy years or more? Longer than I have been alive? It’s just not us, it’s not the Rams.”---Mr. Ram Jack Youngblood