As was said by Kirk Morrison on pregame of Seahawk match.....

Don't look at the License Plate on the RB
These guys bring it every week.

Morrison noted just how well the SF 49ers have played without their #1 guys out there
Shanahan gets his guys in position to succeed.

I expect whoever takes the field for the Vikings back there to lit up and ready to roll.

Now....not having Thielen would be an issue in my mind.
But they've played ball without Cook this season already. Add to it that everyone is banged up this late in the go, too.