This is less tactical and more situational based on what I've read from the Lions board.
Stafford played his absolute best when down ~10 points in the 4th quarter. He played his worst when in a "big game" like the playoffs or against a top team.
He will often gun the ball, even close-in causing a lot of drops/overthrows. So maybe play 2 high safety to remove the deep ball and blitz a corner to get pressure? He's not much of a threat to run so maintain gaps and clog the middle?
He often has long lulls for a quarter at a time where he doesn't do much. Not sure if there is a key to knowing when that will be. Some QBs do worse when you drop everyone and they have too much time. Others crumble under bringing the house. Not sure if Stafford has any of those tendencies.
One big scheme difference is that Stafford has generally had guys that are great at fighting for 50/50 balls (golladay, jones, hock). Separation and pinpoint accuracy were less important. Kupp/Woods/Jackson/Jefferson are all precision/timing WRs . Will this align with what Stafford is best at?
Maybe the book against the Rams is to press cover or blanket WRs and take away what Stafford likes to do?
Sounds like I am hating and I definitely don't. Question is how to defend Stafford and I am challenging my brain to what I know/have heard about him.