Lots of good ones already taken.

I'll add another couple from last season on the good side:
Goff bouncing up from his QB sneak to seal the victory over Seattle and that fiery emotion we rarely see from him afterward.
Or Gurley and CJ mimicking Elliot's "spoon-feed" thing as we flipped the table on how the Dallas game was "supposed" to go.

Negative one... hmmmm....
Opening game of 2003 against NYG. Warner fumbled a bunch (team had six... was he responsible for all of them? I think so...) and threw an INT as well. He was concussed. Basically ended his career as a Ram. On top of the SB36 loss and the 2002 slump... ugh. The season went on to be a pretty good one, but Warner would never helm a Rams team again. When you think about Dickerson, Bettis, SJax... all guys who could have accomplished so much more with the Rams under better circumstances... well, Warner's departure is another "iconic" moment in that vein.