Was in Co. Last week. The weed..my god...when you need some glass contraption, dental tools, a blow torch and some ridiculously highly concertated wax or shatter, you might be more crack head than stoner. Just saying.
Anyway, the temps look good, should be no problem there. Denver is approx 5300ish miles above sea level. The air is thin, but not horrible. I spent most of my time In a little town called Leadville. 10000 ft or two miles high. Altitude sickness definately an issue up that high. Felt much better once I returned to Denver. So yeah, its a factor but nothing arriving a day or so early (if possible) wont fix. Plus they will have plenty of O2 available for the players Im sure. No snow forecasted, crisp but not cold. Tough place to play, but Rams are road warriors. If they dont look past the Broncos and bring at least their B+ game, they should handle Denver