It should make no difference in McVay's decision that the game is in LA against the Niners.
I remember in 1967 the Rams were playing the Colts to decide the Coastal Division champ on the last game of the season. The Rams destroyed the Colts as the Fearsome Foursome totally dominating Johny U and company.
At the same time the Packers were playing in Pittsburgh against a bad Steelers team and rested all their starters and lost. No one cared. The following week the Packer beat the crap out of the Rams in GB.
Just some context.
~ max ~
“The consciousness of good intentions disdains ambiguity.” - Alexander Hamilton