I do think that the Rams being at home will be a help. Not huge, but some.
If only the fans in LA were more numerous and loud. But hey....this is LaLaLand.
I sure hope that the new stadium has been designed to reflect/amplify sound back to the field the way the Seattle stadium was.
And, I admit that the Coliseum is a tough venue for a Pro team due to it's enormous seating capacity. Even when you have 65,000 people show up, it looks empty. And it wasn't designed to maximize noise.
Nonetheless, being at home keeps the Rams more rested and able to get treatment down to the last minute among other home field advantages even if the crowd noise doesn't help like it does in most other places.