Barring the any given Sunday philosophy, the Rams are going to handily defeat Seattle at home on Sunday.
Seattle is a C+ or B- team. The Rams know all there is to know about how to play Seattle. The bigger problem is not how the Rams defend Seattle, it's Seattle's problem of how to defend the Rams. Seattle is not a team that will be putting up a lot of points on you. The Rams can put up a lot of points against almost anyone.
The Rams are healthy, no doubt pissed off after losing to the Saints, and McVay has yet to let the Rams lose two in a row.
I think the Rams win wire to wire against Seattle.