Niners defense is very suspect to me.
The Cardinals had one of the best defenses in the NFL last year. They went 7-9 without David Johnson and with Stanton and Gabbert.
I do think the 49ers will score...but, their best pass rusher last year was Elvis Dumervil and he is gone from what was a below average pass rush.
The Cardinals have holes but if Bradford can stay healthy long enough, they will compete. If not, I could still see them getting 6-7 wins with Rosen.
I think Seattle still has issues..and their defense is no where near where it was. To me...they have Wilson. No one scares me at the WR or RB positions.