Positives include their ability to slow the rush with the threat of the read option, where the DEs cannot pin their ears back. They can typically have quicker impact than the pocket guys for a coordinator who can utilize them correctly.
Negatives include a shorter life span if they don't transition to a pocket passer. And by pocket passer I include QBs who keep their athletic ability restricted to scramble drills with intent to throw and avoiding contact for the most part. You just don't want to be a primary run threat for too many snaps in this league, because you are taking a beating and living on borrowed time. Another negative tends to be more simplified reads as their systems capitalize on ability and don't require them to progress the way NFL teams would prefer, and tbh I am not sure to what extent that is true in his case.
He is interesting, though. Here's a quote by his OC
I read recently:
“I think Deshaun has worked his whole life to be a quarterback, and I don’t think he wants to be pigeonholed into one aspect of the position,” Clemson co-offensive coordinator Tony Elliott said. “He wants to be respected for what quarterbacks are respected for: His ability to make decisions, his ability to make throws, and that’s what Deshaun wants people to focus on. He's gifted enough to run and athletic enough to extend some plays, but he’s worked his whole life to be considered just a quarterback.”