Quick answer: All over the place.
If McVay can use Kupp and Puka as interchangeable parts, and run them in bunches and stacks = defender's nightmare. Puka split left, Kupp split right or in the slot, Tutu taking up the leftover spot, = defender's nightmare.
Stafford would only need 2 secs to read & launch. YAC potential for any of those three with open grass in front of them = defense coordinator's nightmare.
Sleepless nights in the cities we visit.